A study reveals the effects of applying autologous adipose tissue-derived stromal vascular fraction (SVF) cells in patients with osteoarthritis. SFV contains a large amount of stem cells and other regenerative cells, and can be easily obtained from loose connective tissue that is associated with adipose tissue.
Safety and clinical efficiency of freshly isolated autologous SVF cells are evaluated in a controlled study of patients with grade 2-4 degenerative osteoarthritis. A total of 1,128 patients underwent standard liposuction, when SVF cells were isolated and prepared for application into joints. 1,114 patients were then followed for an average of 17.2 months.
Patients were to be evaluated based on pain, non-steroid analgesic usage, limping, extent of joint movement and stiffness. The evaluations were done before the procedure, as well as three, six and twelve months after the treatment. At least 75% score improvement was noticed in 63% of patients and at least a 50% score improvement was noticed in 91% of patients twelve months after the SVF cell therapy. Obesity and higher grade osteoarthritis were revealed to be associated with slower healing in patients.
This promising approach to treating patients with osteoarthritis is safe and cost effective. Not only that, but it relies only on autologous cells, meaning there is less of a change of rejection because the cells are gathered from that persons own body.
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